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Literature summary for 4.2.99.18 extracted from
- Schizosaccharomyces pombe encodes a mutated AP endonuclease 1 (2011), DNA Repair, 10, 296-305.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | P50525 | identification of a new 5' exon, exon 1, in the apn1 gene. The inactivity of Schizosaccharomyces pombe Apn1 is due to a nonsense mutation in the fifth codon of this exon. Reversion of this mutation restores the AP endonuclease activity of Apn1. The apn1 nonsense mutation is only found in laboratory strains derived from L972 h- and not in unrelated isolates of Schizosaccharomyces pombe. Since all Schizosaccharomyces pombe laboratory strains originate from L972 h-, it appears that all experiments involving Schizosaccharomyces pombe have been conducted in an apn1- mutant strain with a corresponding DNA repair deficiency | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| APN1 | - |
Schizosaccharomyces pombe |
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Release 2023.1 (January 2023)
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