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Literature summary for 4.2.3.9 extracted from

  • Faraldos, J.A.; Allemann, R.K.
    Inhibition of (+)-aristolochene synthase with iminium salts resembling eudesmane cation (2011), Org. Lett., 13, 1202-1205.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(4aS,7S)-1,4a-dimethyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium iodide inhibitor mimics transition state associated with the cyclization of (-)-germacrene A to eudesmane cation, competitive Penicillium roqueforti
(4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium chloride inhibitor mimics transition state associated with the cyclization of (-)-germacrene A to eudesmane cation, competitive Penicillium roqueforti

Organism

Organism UniProt Comment Textmining
Penicillium roqueforti Q03471
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0284
-
(4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium chloride pH not specified in the publication, temperature not specified in the publication Penicillium roqueforti
0.219
-
(4aS,7S)-1,4a-dimethyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium iodide pH not specified in the publication, temperature not specified in the publication Penicillium roqueforti