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Literature summary for 4.2.3.9 extracted from

  • Hohn, T.M.; Plattner, R.D.
    Purification and characterization of the sesquiterpene cyclase aristolochene synthase from Penicillium roqueforti (1989), Arch. Biochem. Biophys., 272, 137-143.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
Mn2+ above 0.01 mM, activation below Penicillium roqueforti
additional information no effect: phosphate up to concentrations of 5.0 mM Penicillium roqueforti

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00055
-
 trans,trans-farnesyl diphosphate pH 7.5 Penicillium roqueforti

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, maximal activity at 3 mM Penicillium roqueforti
Mn2+ 0.01 mM, can partially replace Mg2+, inhibition above Penicillium roqueforti

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 1 * 37000, SDS-PAGE Penicillium roqueforti
48000
-
 gel filtration Penicillium roqueforti

Organism

Organism UniProt Comment Textmining
Penicillium roqueforti
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Penicillium roqueforti

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.07
-
-
 Penicillium roqueforti

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans,trans-farnesyl diphosphate
-
 Penicillium roqueforti aristolochene + diphosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 37000, SDS-PAGE Penicillium roqueforti

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3 7.5
-
 Penicillium roqueforti