Literature summary for 4.2.3.75 extracted from

Schmidt, C.O.; Bouwmeester, H.J.; Franke, S.; Konig, W.A.
Mechanisms of the biosynthesis of sesquiterpene enantiomers (+)- and (-)-germacrene D in Solidago canadensis (1999), Chirality, 11, 353-362.

No PubMed abstract available

Search for more literature for 4.2.3.75

Organism

Organism	UniProt	Comment	Textmining
Solidago canadensis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Solidago canadensis

Reaction

Reaction	Comment	Organism	Reaction ID
(2E,6E)-farnesyl diphosphate = (-)-germacrene D + diphosphate	action of (-)-germacrene D synthase involves a 1,3-hydride shift. Pro-R-H-1 of the substrate (2E,6E)-farnesyl diphosphate becomes H-11 of (-)-germacrene D, while pro-S-H-1 of (2E,6E)-farnesyl diphosphate becomes H-6 of (-)-germacrene D and H-10 of (2E,6E)-farnesyl diphosphate becomes H-7 of (-)-germacrene D	Solidago canadensis	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2E,6E)-farnesyl diphosphate	-	Solidago canadensis	(-)-germacrene D + diphosphate	catalyzes the formation of enantiomerically pure (-)-germacrene D	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)