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Literature summary for 4.2.3.73 extracted from

  • Scholtmeijer, K.; Cankar, K.; Beekwilder, J.; Woesten, H.A.; Lugones, L.G.; Bosch, D.
    Production of (+)-valencene in the mushroom-forming fungus S. commune (2014), Appl. Microbiol. Biotechnol., 98, 5059-5068.
    View publication on PubMed

Application

Application Comment Organism
synthesis Introduction of a valencene synthase gene into mushroom-forming fungus Schizophyllum commune results in production of the sesquiterpene (+)-valencene, both in mycelium and in fruiting bodies. Levels of (+)-valencene in culture media of strains containing a mutated RGS regulatory protein gene are increased fourfold compared to those in wild-type transformants. Up to 16 mg l/1 (+)-valencene can be produced. The amount of (+)-valencene containing n-dodecane recovered from the culture medium increases six- to sevenfold in the mutant strains due to the absence of schizophyllan Callitropsis nootkatensis

Cloned(Commentary)

Cloned (Comment) Organism
expression in Schizophyllum commune Callitropsis nootkatensis

Organism

Organism UniProt Comment Textmining
Callitropsis nootkatensis V9N2L5
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