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Literature summary for 4.2.3.70 extracted from
- The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases (2006), Arch. Biochem. Biophys., 454, 123-136.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | may substitute for Mn2+ at 0.1 mM, inhibitory above | Pogostemon cablin |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00445 | - |
(2E,6E)-farnesyl diphosphate | pH 7.0, 30°C | Pogostemon cablin | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | preferred, maximum activity at 1 mM | Pogostemon cablin | |
| Mn2+ | may substitute for Mn2+ at 0.1 mM, inhibitory above | Pogostemon cablin | |
| additional information | divalent cation required | Pogostemon cablin |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | - |
x * 55000, SDS-PAGE | Pogostemon cablin |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pogostemon cablin | Q49SP3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2E,6E)-farnesyl diphosphate + H2O | - |
Pogostemon cablin | patchoulol + diphosphate | plus at least 13 additional sesquiterpene products | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 55000, SDS-PAGE | Pogostemon cablin |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TPS177 | - |
Pogostemon cablin |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Pogostemon cablin |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | - |
30% of maximum activity | Pogostemon cablin |
| 30 | - |
less than 60% of maximum activity | Pogostemon cablin |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00043 | - |
(2E,6E)-farnesyl diphosphate | pH 7.0, 30°C | Pogostemon cablin | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.5 | - |
Pogostemon cablin |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
dramatical reduction in activity below | Pogostemon cablin |
| 8 | - |
75% of maximum activity | Pogostemon cablin |
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