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Literature summary for 4.2.3.6 extracted from

  • Kumari, I.; Chaudhary, N.; Sandhu, P.; Ahmed, M.; Akhter, Y.
    Structural and mechanistic analysis of engineered trichodiene synthase enzymes from Trichoderma harzianum towards higher catalytic activities empowering sustainable agriculture (2016), J. Biomol. Struct. Dyn., 34, 1176-1189 .
    View publication on PubMed
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Protein Variants

Protein Variants Comment Organism
D109E the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum
D109E/D248Y the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum
D248Y the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate Trichoderma harzianum
-
 trichodiene + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Trichoderma harzianum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate
-
 Trichoderma harzianum trichodiene + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
tri5
-
 Trichoderma harzianum