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Literature summary for 4.2.3.48 extracted from

  • Aharoni, A.; Giri, A.P.; Verstappen, F.W.; Bertea, C.M.; Sevenier, R.; Sun, Z.; Jongsma, M.A.
    Schwab, W.; Bouwmeester, H.J.: Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species (2004), Plant Cell, 16, 3110-3131.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.3.48

Cloned(Commentary)

Cloned (Comment) Organism
recombinant FaNES1 enzyme produced in Escherichia coli cells is capable of generating both linalool and nerolidol when supplied with geranyl diphosphate or farnesyl diphosphate, respectively Fragaria x ananassa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0081
-
 (2E,6E)-farnesyl diphosphate
-
 Fragaria x ananassa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O Fragaria x ananassa
-
 (3S,6E)-nerolidol + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Fragaria x ananassa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit FaNES1 is strongly expressed in cultivated strawberry (octaploid) varieties but hardly expressed at all in wild strawberry species. Increase in FaNES1 transcript levels during fruit ripening Fragaria x ananassa
-
additional information no expression detected in leaf tissue Fragaria x ananassa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O
-
 Fragaria x ananassa (3S,6E)-nerolidol + diphosphate
-
 ?
(2E,6E)-farnesyl diphosphate + H2O the enzyme also converts geranyl diphosphate to (3S)-linalool, EC 4.2.3.25 (S-linalool synthase) Fragaria x ananassa (3S,6E)-nerolidol + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
FaNES1
-
 Fragaria x ananassa

Expression

Organism Comment Expression
Fragaria x ananassa increase in FaNES1 transcript levels during fruit ripening up