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Literature summary for 4.2.3.24 extracted from

  • Alam, P.; Kiran, U.; Ahmad, M.M.; Kamaluddin, M.M.; Khan, M.A.; Jhanwar, S.; Abdin, M.
    Isolation, characterization and structural studies of amorpha - 4, 11-diene synthase (ADS(3963)) from Artemisia annua L (2010), Bioinformation, 4, 421-429.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
3D-modeling of structure. Predicted model shows that the putative ADS3963 protein contains 72% of alpha-helices, 23% beta-turns and 26% of random coils. Based on docking studies with substrate farnesyl diphosphate, the stretches Ala321-Ala324-Lys-398, Ala234-Val237-Phe283-Thr286-Tyr-287, Ser94-Met95-Trp141-Trp430-Asn434, Ser94-Arg96-Glu104-Leu107-Lys142-Lys431, Lys137-Arg143-Ile147-Ala150-Gln151-Leu478 and Ser218-Gly219-Tyr224-Arg228-Cys352-Met356-Aln450 may constitute to substrate binding Artemisia annua

Organism

Organism UniProt Comment Textmining
Artemisia annua Q9AR04 presence of conserved domain DDxxD and a motif SlwD, a casein kinase II phosphorylation domain site at position 104-107 in ADS3963 protein
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Source Tissue

Source Tissue Comment Organism Textmining
leaf
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Artemisia annua
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Subunits

Subunits Comment Organism
? x 62200, calculated Artemisia annua

Synonyms

Synonyms Comment Organism
ADS3963
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Artemisia annua

pI Value

Organism Comment pI Value Maximum pI Value
Artemisia annua calculated
-
5.3