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Literature summary for 4.2.3.24 extracted from

  • Kim, S.H.; Chang, Y.J.; Kim, S.U.
    Tissue specificity and developmental pattern of amorpha-4,11-diene synthase (ADS) proved by ADS promoter-driven GUS expression in the heterologous plant, Arabidopsis thaliana (2008), Planta Med., 74, 188-193.
    View publication on PubMed

Application

Application Comment Organism
medicine amorpha-4,11-diene is a presursor of artemisinin, artemisinin and derivates are used for the treatment of malaria Artemisia annua

Cloned(Commentary)

Cloned (Comment) Organism
the open reading frame of amorpha-4,11-diene synthase is fused to the green fluorescent proten reporter gene for introducing into the Arabidopsis protoplasts Artemisia annua

Localization

Localization Comment Organism GeneOntology No. Textmining
protoplast
-
Artemisia annua
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-trans,6-trans-farnesyl diphosphate Artemisia annua
-
amorpha-4,11-diene + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Artemisia annua
-
the expression pattern of the GUS reporter gene, driven by the promoter of Artemisia annua ADS, is investigated in the model plant Arabidopsis thaliana
-

Source Tissue

Source Tissue Comment Organism Textmining
flower young flower Artemisia annua
-
leaf juvenile leaf Artemisia annua
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-trans,6-trans-farnesyl diphosphate
-
Artemisia annua amorpha-4,11-diene + diphosphate
-
?

Synonyms

Synonyms Comment Organism
ADS
-
Artemisia annua
amorpha-4,11-diene synthase
-
Artemisia annua