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Literature summary for 4.2.3.23 extracted from

  • Majdi, M.; Liu, Q.; Karimzadeh, G.; Malboobi, M.A.; Beekwilder, J.; Cankar, K.; Vos, R.; Todorovic, S.; Simonovic, A.; Bouwmeester, H.
    Biosynthesis and localization of parthenolide in glandular trichomes of feverfew (Tanacetum parthenium L. Schulz Bip.) (2011), Phytochemistry, 72, 1739-1750.
    View publication on PubMed
Search for more literature for 4.2.3.23

Application

Application Comment Organism
analysis in GC-MS analysis of reaction products, beta-elemene is identified as product of farnesyl diphosphate reaction. beta-Elemene is the Cope rearrangement product of germacrene A that is formedupon injection into the hot injection port of the GC-MS Tanacetum parthenium

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Tanacetum parthenium

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64500
-
 x * 64500, calculated Tanacetum parthenium

Organism

Organism UniProt Comment Textmining
Tanacetum parthenium F8UL80
-
-
Tanacetum parthenium L. Schulz Bip. F8UL80
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower GAS expression in flowers is more than 4fold higher than in leaves and 25fold higher than in stems. In flowers the highest expression wais observed in the biosynthetically most active stages of flower development Tanacetum parthenium
-
leaf GAS expression in flowers is more than 4fold higher than in leaves and 25fold higher than in stems Tanacetum parthenium
-
additional information expressed in all aerial tissues, the highest expression is observed in tissues that contain high concentrations of parthenolide Tanacetum parthenium
-
stem GAS expression in flowers is more than 4fold higher than in leaves and 25fold higher than in stems Tanacetum parthenium
-
trichome high expression of GAS in glandular trichomes, which also contain the highest concentration of parthenolide Tanacetum parthenium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate
-
 Tanacetum parthenium (+)-(R)-germacrene A + diphosphate in GC-MS analysis, beta-elemene is identified as product. beta-Elemene is the Cope rearrangement product of germacrene A that is formed upon injection into the hot injection port of the GC-MS ?
(2E,6E)-farnesyl diphosphate
-
 Tanacetum parthenium L. Schulz Bip. (+)-(R)-germacrene A + diphosphate in GC-MS analysis, beta-elemene is identified as product. beta-Elemene is the Cope rearrangement product of germacrene A that is formed upon injection into the hot injection port of the GC-MS ?

Subunits

Subunits Comment Organism
? x * 64500, calculated Tanacetum parthenium

Synonyms

Synonyms Comment Organism
GAS
-
 Tanacetum parthenium

pI Value

Organism Comment pI Value Maximum pI Value
Tanacetum parthenium calculated
-
 5