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Literature summary for 4.2.3.22 extracted from

  • Jiang, J.; He, X.; Cane, D.E.
    Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin (2006), J. Am. Chem. Soc., 128, 8128-8129.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
for expression in Escherichia coli Streptomyces coelicolor

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ suppresses the formation of geosmin by factor 3 or more Streptomyces coelicolor
Fe2+ suppresses the formation of geosmin by factor 3 or more Streptomyces coelicolor

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor Q9X839
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O
-
Streptomyces coelicolor (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate trans-1,10-dimethyl-trans-9-decalol ?

Synonyms

Synonyms Comment Organism
germacradienol/germacrene D synthase
-
Streptomyces coelicolor

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
activity assay Streptomyces coelicolor