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Literature summary for 4.2.3.190 extracted from

  • Brueckner, K.; Bozic, D.; Manzano, D.; Papaefthimiou, D.; Pateraki, I.; Scheler, U.; Ferrer, A.; de Vos, R.C.; Kanellis, A.K.; Tissier, A.
    Characterization of two genes for the biosynthesis of abietane-type diterpenes in rosemary (Rosmarinus officinalis) glandular trichomes (2014), Phytochemistry, 101, 52-64 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Salvia rosmarinus W8QEG7 cf. EC 4.2.3.131
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Salvia rosmarinus W8QMF8 cf. EC 4.2.3.131
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Source Tissue

Source Tissue Comment Organism Textmining
trichome glandular trichome Salvia rosmarinus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate
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Salvia rosmarinus manoyl oxide + diphosphate
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?
additional information bifunctional enzyme, catalyzing the reaction of (+)-copalyl diphosphate to miltiradiene, EC 4.2.3.131 and, in combination with Nicotinana tabacum CPS2 the synthesis of manoyl oxide Salvia rosmarinus ?
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?

Synonyms

Synonyms Comment Organism
kaurene synthase-like 1
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Salvia rosmarinus
kaurene synthase-like 2
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Salvia rosmarinus
KSL1
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Salvia rosmarinus
KSL2
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Salvia rosmarinus

General Information

General Information Comment Organism
physiological function coexpression of Nicotiana tabacum CPS2 and isoofrm KSL1 in Nicotiana benthamiana leaves results in the production of manoyl oxide Salvia rosmarinus