Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.3.154 extracted from

  • Balskus, E.P.; Walsh, C.T.
    The genetic and molecular basis for sunscreen biosynthesis in cyanobacteria (2010), Science, 329, 1653-1656.
    View publication on PubMed
Search for more literature for 4.2.3.154

Activating Compound

Activating Compound Comment Organism Structure
Co2+ the enzyme requires a divalent metal ion (Zn2+ or Co2+) Nostoc punctiforme
Zn2+ the enzyme requires a divalent metal ion (Zn2+ or Co2+) Nostoc punctiforme

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-sedoheptulose 7-phosphate Nostoc punctiforme the enzyme is involved in the biosynthesis of the sunscreen compound shinorine demethyl-4-deoxygadusol + phosphate + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Nostoc punctiforme
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-sedoheptulose 7-phosphate the enzyme is involved in the biosynthesis of the sunscreen compound shinorine Nostoc punctiforme demethyl-4-deoxygadusol + phosphate + H2O
-
 ?
D-sedoheptulose 7-phosphate
-
 Nostoc punctiforme demethyl-4-deoxygadusol + phosphate + H2O demethyl-4-deoxygadusol i.e. 2,3,5-trihydroxy-5-(hydroxymethyl)cyclohex-2-en-1-one ?

Cofactor

Cofactor Comment Organism Structure
NAD+ the enzyme requires a NAD+ cofactor, which is transiently reduced during the reaction Nostoc punctiforme

General Information

General Information Comment Organism
metabolism the enzyme is involved in the biosynthesis of the sunscreen compound shinorine Nostoc punctiforme