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Literature summary for 4.2.3.146 extracted from

  • Kim, S.Y.; Zhao, P.; Igarashi, M.; Sawa, R.; Tomita, T.; Nishiyama, M.; Kuzuyama, T.
    Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases (2009), Chem. Biol., 16, 736-743.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Streptomyces melanosporofaciens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranylgeranyl diphosphate + H2O Streptomyces melanosporofaciens
-
cyclooctat-9-en-7-ol + diphosphate
-
?
geranylgeranyl diphosphate + H2O Streptomyces melanosporofaciens MI614-43F2
-
cyclooctat-9-en-7-ol + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces melanosporofaciens
-
-
-
Streptomyces melanosporofaciens MI614-43F2
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + H2O
-
Streptomyces melanosporofaciens cyclooctat-9-en-7-ol + diphosphate
-
?
geranylgeranyl diphosphate + H2O
-
Streptomyces melanosporofaciens MI614-43F2 cyclooctat-9-en-7-ol + diphosphate
-
?

Synonyms

Synonyms Comment Organism
CotB2
-
Streptomyces melanosporofaciens