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Literature summary for 4.2.3.13 extracted from
- Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol (2006), Proc. Natl. Acad. Sci. USA, 103, 18054-18059.
Application
| Application | Comment | Organism |
|---|---|---|
| agriculture | RNAi is used to disrupt gossypol biosynthesis in cotton seed tissue by interfering with the expression of the delta-cadinene synthase gene during seed development. It is possible to significantly reduce cottonseed-gossypol levels in a stable and heritable manner. The levels of gossypol and related terpenoids in the foliage and floral parts are not diminished, and thus their potential function in plant defense against insects and diseases remains untouched. A targeted genetic modification, applied to an underutilized agricultural byproduct, provides a mechanism to open up a new source of nutrition for hundreds of millions of people | Gossypium hirsutum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gossypium hirsutum | - |
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