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Literature summary for 4.2.3.125 extracted from

  • Agger, S.; Lopez-Gallego, F.; Schmidt-Dannert, C.
    Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus (2009), Mol. Microbiol., 72, 1181-1195.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene cop3, DNA and amino acid sequence determination and analysis, phylogenetic analysis, recombinant expression in Escherichia coli strain JM109 leading to production of alpha-muurolene Coprinopsis cinerea

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate Coprinopsis cinerea
-
alpha-muurolene + diphosphate
-
?
(2E,6E)-farnesyl diphosphate Coprinopsis cinerea ATCC MYA-4618
-
alpha-muurolene + diphosphate
-
?
additional information Coprinopsis cinerea product profiling by GC-MS analysis, overview. alpha-Muurolene is the major terpenoid compound detected in Cop3 cultures, accounting for about 30% of the total sesquiterpenes detected. Significant amounts of beta-elemene, gamma-muurolene, germacrene D, and delta-cadinene are synthesized in the headspace of Cop3 cultures ?
-
?
additional information Coprinopsis cinerea ATCC MYA-4618 product profiling by GC-MS analysis, overview. alpha-Muurolene is the major terpenoid compound detected in Cop3 cultures, accounting for about 30% of the total sesquiterpenes detected. Significant amounts of beta-elemene, gamma-muurolene, germacrene D, and delta-cadinene are synthesized in the headspace of Cop3 cultures ?
-
?

Organism

Organism UniProt Comment Textmining
Coprinopsis cinerea A8NE23 gene cop3
-
Coprinopsis cinerea ATCC MYA-4618 A8NE23 gene cop3
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate
-
Coprinopsis cinerea alpha-muurolene + diphosphate
-
?
(2E,6E)-farnesyl diphosphate
-
Coprinopsis cinerea alpha-muurolene + diphosphate recombinant Escherichia coli produces alpha-muurolene to 30% of total terpenoid compounds, but also other sesquiterpenes ?
(2E,6E)-farnesyl diphosphate
-
Coprinopsis cinerea ATCC MYA-4618 alpha-muurolene + diphosphate
-
?
(2E,6E)-farnesyl diphosphate
-
Coprinopsis cinerea ATCC MYA-4618 alpha-muurolene + diphosphate recombinant Escherichia coli produces alpha-muurolene to 30% of total terpenoid compounds, but also other sesquiterpenes ?
additional information product profiling by GC-MS analysis, overview. alpha-Muurolene is the major terpenoid compound detected in Cop3 cultures, accounting for about 30% of the total sesquiterpenes detected. Significant amounts of beta-elemene, gamma-muurolene, germacrene D, and delta-cadinene are synthesized in the headspace of Cop3 cultures Coprinopsis cinerea ?
-
?
additional information product profiling by GC-MS analysis, overview. alpha-Muurolene is the major terpenoid compound detected in Cop3 cultures, accounting for about 30% of the total sesquiterpenes detected. Significant amounts of beta-elemene, gamma-muurolene, germacrene D, and delta-cadinene are synthesized in the headspace of Cop3 cultures Coprinopsis cinerea ATCC MYA-4618 ?
-
?

Synonyms

Synonyms Comment Organism
Cop3
-
Coprinopsis cinerea

General Information

General Information Comment Organism
additional information Cop3 is a terpene synthase Coprinopsis cinerea