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Literature summary for 4.2.3.12 extracted from

  • Takikawa, S.; Curtius, H.Ch.; Redweik, U.; Ghisla, S.
    Purification of 6-pyruvoyl-tetrahydropterin synthase from human liver (1986), Biochem. Biophys. Res. Commun., 134, 646-651.
    View publication on PubMed
Search for more literature for 4.2.3.12

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19000
-
 x * 19000, SDS-PAGE Homo sapiens
19000
-
 4 * 19000, SDS-PAGE Homo sapiens
83000
-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7,8-dihydroneopterin triphosphate Homo sapiens assay at 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate precipitation, hydroxyapatite column, gel filtration, DEAE-Fractogel 650S column, SDS-PAGE Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Storage Stability

Storage Stability Organism
-20ºC and -70ºC, Tris HCl, several months, stable Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7,8-dihydroneopterin triphosphate
-
 Homo sapiens 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
 ?
7,8-dihydroneopterin triphosphate assay at Homo sapiens 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 19000, SDS-PAGE Homo sapiens
tetramer 4 * 19000, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens