Literature summary for 4.2.3.118 extracted from

Koeksal, M.; Chou, W.K.; Cane, D.E.; Christianson, D.W.
Structure of 2-methylisoborneol synthase from Streptomyces coelicolor and implications for the cyclization of a noncanonical C-methylated monoterpenoid substrate (2012), Biochemistry, 51, 3011-3020.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Streptomyces coelicolor

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with substrate analogues geranyl-S-thiolodiphosphate and 2-fluorogeranyl diphosphate at 1.80 and 1.95 A resolution, respectively. MIBS adopts the tertiary structure of a class I terpenoid cyclase. The dimeric quaternary structure is different, the active sites in the MIBS dimer are oriented in parallel fashion and the dimer interface in MIBS is formed by helices D1, D2	Streptomyces coelicolor

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
47000	-	x * 47000, calculated	Streptomyces coelicolor
80000	90000	gel filtration	Streptomyces coelicolor
150000	-	PAGE	Streptomyces coelicolor

Organism

Organism	UniProt	Comment	Textmining
Streptomyces coelicolor	Q9F1Y6	-	-

Subunits

Subunits	Comment	Organism
multimer	x * 47000, calculated	Streptomyces coelicolor

Synonyms

Synonyms	Comment	Organism
MIBS	-	Streptomyces coelicolor

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Release 2023.1 (January 2023)