Literature summary for 4.2.3.118 extracted from

Giglio, S.; Chou, W.K.; Ikeda, H.; Cane, D.E.; Monis, P.T.
Biosynthesis of 2-methylisoborneol in cyanobacteria (2010), Environ. Sci. Technol., 45, 992-998.

Search for more literature for 4.2.3.118

Organism

Organism	UniProt	Comment	Textmining
Pseudanabaena limnetica	E9NH28	-	-
Pseudanabaena limnetica Castaic Lake	E9NH28	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(E)-2-methylgeranyl diphosphate + H2O	-	Pseudanabaena limnetica	2-methylisoborneol + diphosphate	major reaction product	?
(E)-2-methylgeranyl diphosphate + H2O	-	Pseudanabaena limnetica Castaic Lake	2-methylisoborneol + diphosphate	major reaction product	?

Synonyms

Synonyms	Comment	Organism
MIBS	-	Pseudanabaena limnetica

General Information

General Information	Comment	Organism
physiological function	biosynthesis of 2-methylisoborneol in cyanobacteria is a result of 2 key reactions, a S-adenosylmethionine-dependent methylation of the monoterpene precursor geranyl diphosphate to 2-methylgeranyl diphosphate catalyzed by geranyl diphosphate 2-methyltransferase, and further cyclization of 2-methylgeranyl diphosphate to 2-methylisoborneol catalyzed by 2-methylisoborneol synthase as part of a 2-methylisoborneol operon	Pseudanabaena limnetica

kcat/KM [mM/s]

kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Comment	Organism	Structure
1.45	-	(E)-2-methylgeranyl diphosphate	temperature not specified in the publication, pH not specified in the publication	Pseudanabaena limnetica

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Release 2023.1 (January 2023)