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Literature summary for 4.2.3.110 extracted from

  • Cao, Y.; Zhang, H.; Liu, H.; Liu, W.; Zhang, R.; Xian, M.; Liu, H.
    Biosynthesis and production of sabinene current state and perspectives (2018), Appl. Microbiol. Biotechnol., 102, 1535-1544 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
sequence comparisons and phylogenetic analysis Citrus unshiu
sequence comparisons and phylogenetic analysis Citrus jambhiri
sequence comparisons and phylogenetic analysis Salvia officinalis
sequence comparisons and phylogenetic analysis Picea sitchensis
sequence comparisons and phylogenetic analysis Salvia pomifera
sequence comparisons and phylogenetic analysis Thuja plicata
sequence comparisons and phylogenetic analysis Murraya koenigii
sequence comparisons and phylogenetic analysis Hedychium coronarium

Protein Variants

Protein Variants Comment Organism
additional information strategies in engineering sabinene production, overview Citrus unshiu
additional information strategies in engineering sabinene production, overview Citrus jambhiri
additional information strategies in engineering sabinene production, overview Salvia officinalis
additional information strategies in engineering sabinene production, overview Picea sitchensis
additional information strategies in engineering sabinene production, overview Thuja plicata
additional information strategies in engineering sabinene production, overview Murraya koenigii
additional information strategies in engineering sabinene production, overview Phomopsis sp. EC-4
additional information strategies in engineering sabinene production, overview. Biosynthetic pathway using both the non-mevalonate MEP and mevalonate MVA pathways combining the geranyl diphosphate synthase genes and sabinene synthase from Salvia pomifera, and engineering native Erg20p into a GPP synthase and heterologous expression of sabinene synthase from Salvia pomifera Salvia pomifera

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Picea sitchensis 9507
-
chloroplast
-
Murraya koenigii 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranyl diphosphate Citrus unshiu
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Citrus jambhiri
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Salvia officinalis
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Picea sitchensis
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Salvia pomifera
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Thuja plicata
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Murraya koenigii
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Phomopsis sp. EC-4
-
(+)-sabinene + diphosphate
-
?
geranyl diphosphate Hedychium coronarium
-
(+)-sabinene + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Citrus jambhiri
-
-
-
Citrus unshiu
-
-
-
Hedychium coronarium
-
-
-
Murraya koenigii A0A1U9M7Y9
-
-
Phomopsis sp. EC-4
-
-
-
Picea sitchensis F1CKJ1
-
-
Salvia officinalis O81193
-
-
Salvia pomifera A6XH06
-
-
Thuja plicata R9WS05
-
-

Reaction

Reaction Comment Organism Reaction ID
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Citrus unshiu
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Citrus jambhiri
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Salvia officinalis
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Picea sitchensis
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Salvia pomifera
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Thuja plicata
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Murraya koenigii
geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Hedychium coronarium

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Citrus unshiu
-
leaf
-
Citrus jambhiri
-
leaf
-
Salvia officinalis
-
leaf
-
Picea sitchensis
-
leaf
-
Salvia pomifera
-
leaf
-
Thuja plicata
-
leaf
-
Murraya koenigii
-
leaf
-
Hedychium coronarium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranyl diphosphate
-
Citrus unshiu (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Citrus jambhiri (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Salvia officinalis (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Picea sitchensis (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Salvia pomifera (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Thuja plicata (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Murraya koenigii (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Phomopsis sp. EC-4 (+)-sabinene + diphosphate
-
?
geranyl diphosphate
-
Hedychium coronarium (+)-sabinene + diphosphate
-
?
additional information the enzyme produces also (-)-sabinene Picea sitchensis ?
-
?
additional information the enzyme produces also (-)-sabinene Murraya koenigii ?
-
?

Synonyms

Synonyms Comment Organism
CjSabS2
-
Citrus jambhiri
CuSabS2
-
Citrus unshiu
HcSabS
-
Hedychium coronarium
MkSabS
-
Murraya koenigii
MKTPS1
-
Murraya koenigii
MKTPS1
-
Phomopsis sp. EC-4
PsSabS1
-
Picea sitchensis
PsSabS2
-
Picea sitchensis
SaBS
-
Citrus unshiu
SaBS
-
Citrus jambhiri
SaBS
-
Salvia officinalis
SaBS
-
Picea sitchensis
SaBS
-
Salvia pomifera
SaBS
-
Thuja plicata
SaBS
-
Murraya koenigii
SaBS
-
Hedychium coronarium
SoSabS2
-
Salvia officinalis
SpSabS2
-
Salvia pomifera
SSS
-
Picea sitchensis
TPS-sab
-
Picea sitchensis
TpSabS
-
Thuja plicata

Expression

Organism Comment Expression
Hedychium coronarium strategies in engineering sabinene production, overview additional information

General Information

General Information Comment Organism
physiological function the endophytic fungus, Phomopsis sp. EC-4, shows the ability to emit sabinene as a primary component of its volatile organic compounds Phomopsis sp. EC-4