Literature summary for 4.2.3.108 extracted from

Demissie, Z.A.; Cella, M.A.; Sarker, L.S.; Thompson, T.J.; Rheault, M.R.; Mahmoud, S.S.
Cloning, functional characterization and genomic organization of 1,8-cineole synthases from Lavandula (2012), Plant Mol. Biol., 79, 393-411.

Search for more literature for 4.2.3.108

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Lavandula x intermedia

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0057	-	geranyl diphosphate	pH 7.0, 30°C	Lavandula x intermedia

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
63000	-	x * 63000, SDS-PAGE, x * 68500, calculated	Lavandula x intermedia
68500	-	x * 63000, SDS-PAGE, x * 68500, calculated	Lavandula x intermedia

Organism

Organism	UniProt	Comment	Textmining
Lavandula x intermedia	I3WEV8	parents Lavandula angustifolia and Lavandula latifolia	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	the N-terminal 52 amino acids are predicted to code for a transit peptide	Lavandula x intermedia

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
geranyl diphosphate + H2O	-	Lavandula x intermedia	1,8-cineole + diphosphate	80% 1,8-cineole plus 7.9% sabinene, 6.6% alpha-phellandrene, 2.3% limonene, and 1.7% alpha-terpineol	?
neryl diphosphate + H2O	-	Lavandula x intermedia	1,8-cineole + diphosphate	61% 1,8-cineole plus 18.5% sabinene, 8% alpha-phellandrene, 3.3% limonene, and 5.5% alpha-terpineol	?

Subunits

Subunits	Comment	Organism
?	x * 63000, SDS-PAGE, x * 68500, calculated	Lavandula x intermedia

Synonyms

Synonyms	Comment	Organism
CinS	-	Lavandula x intermedia

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.0088	-	geranyl diphosphate	pH 7.0, 30°C	Lavandula x intermedia

Expression

Organism	Comment	Expression
Lavandula x intermedia	LiCINSmRNAlevels parallel the 1,8-cineole content in mature flowers and in developmental stages	additional information

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Release 2023.1 (January 2023)