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Literature summary for 4.2.2.8 extracted from

  • Gu, Y.; Wu, X.; Liu, H.; Pan, Q.; Chen, Y.
    Photoswitchable heparinase III for enzymatic preparation of low molecular weight heparin (2018), Org. Lett., 20, 48-51 .
    View publication on PubMed

Application

Application Comment Organism
synthesis construcution of a photoswitchable biocatalyst consisating of a heparinase III mutant K130C-N,N-dimethylacrylamide-co-4-phenyl azophenyl acrylate copolymer. Upon photoswitch, the enzymatic degradation of heparin can be artificially controlled to produce low molecular weight heparin with more uniform molecular weight and an increase in anticoagulant activity Pedobacter heparinus

Organism

Organism UniProt Comment Textmining
Pedobacter heparinus Q59289
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