Literature summary for 4.2.2.7 extracted from

Dzvova, N.; Colmer-Hamood, J.A.; Griswold, J.A.; Hamood, A.N.
Heparinase is essential for Pseudomonas aeruginosa virulence during thermal injury and infection (2018), Infect. Immun., 86, e00755 .

Search for more literature for 4.2.2.7

Application

Application	Comment	Organism
medicine	in a murine model of thermal injury, mutation of HepP reduces the rate of mortality from 100% for mice infected with wild-type to 7% for mice infected with the mutant strain. Upon intraperitoneal inoculation of the thermally injured mice, the rate of mortality for mice infected the mutant was 0%, whereas it was 66% for mice infected with wild-type. Only wild-type PA14 is recovered from the livers and spleens of infected mice	Pseudomonas aeruginosa

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	A0A0H2ZDM9	-	-
Pseudomonas aeruginosa UCBPP-PA14	A0A0H2ZDM9	-	-

General Information

General Information	Comment	Organism
physiological function	HepP plays a crucial role in the pathogenesis of Pseudomonas aeruginosa PA14 during burn wound infection	Pseudomonas aeruginosa

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Release 2023.1 (January 2023)