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Literature summary for 4.2.2.3 extracted from

  • Ashton, R.S.; Banerjee, A.; Punyani, S.; Schaffer, D.V.; Kane, R.S.
    Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture (2007), Biomaterials, 28, 5518-5525.
    View publication on PubMed

Application

Application Comment Organism
medicine alginate hydrogels can be enzymatically degraded in a controlled and tunable fashion by incorporating poly(lactide-co-glycolide) microspheres loaded with alginate lyase into alginate hydrogels. Neural progenitor cells can be cultured and expanded in vitro in this degradable alginate hydrogel system. A significant increase in the expansion rate of neural progenitor cells cultured in degrading alginate hydrogels versus neural progenitor cells cultured in standard, i.e. non-degrading, alginate hydrogels. Degradable alginate hydrogels encapsulating stem cells may be widely applied to develop novel therapies for tissue regeneration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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