Literature summary for 4.2.2.2 extracted from

Ben-Daniel, B.H.; Bar-Zvi, D.; Tsror Lahkim, L.
Pectate lyase affects pathogenicity in natural isolates of Colletotrichum coccodes and in pelA gene-disrupted and gene-overexpressing mutant lines (2012), Mol. Plant Pathol., 13, 187-197.

Cloned(Commentary)

Cloned (Comment)	Organism
gene pelA from isolate US-41, DNA and amino acid sequence determinationand analysis, expression and promoter analysis, overexpression of CcpelA in Si-60 under the regulation of the promoter Pgpd. The CcpelA promoter of US-41, but not Si-60, contains a putative AreA-binding motif, GATA box. Point mutation in the Si-60 GATA box might prevent positive regulation of CcpelA by the AreA transcription factor, leading to slower gene expression and delayed CcPelA secretion	Colletotrichum coccodes

Cloned (Comment)

Organism

gene pelA from isolate US-41, DNA and amino acid sequence determinationand analysis, expression and promoter analysis, overexpression of CcpelA in Si-60 under the regulation of the promoter Pgpd. The CcpelA promoter of US-41, but not Si-60, contains a putative AreA-binding motif, GATA box. Point mutation in the Si-60 GATA box might prevent positive regulation of CcpelA by the AreA transcription factor, leading to slower gene expression and delayed CcPelA secretion

Colletotrichum coccodes

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of CcpelA gene-disrupted mutants, the mutants show reduced aggressiveness towards tomato fruits and impaired pectate lyase secretion and extracellular activity	Colletotrichum coccodes

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	the enzyme is secreted	Colletotrichum coccodes	-	-

Organism

Organism	UniProt	Comment	Textmining
Colletotrichum coccodes	-	gene pelA	-

General Information

General Information	Comment	Organism
malfunction	construction of CcpelA gene-disrupted mutants, the mutants show reduced aggressiveness towards tomato fruits and impaired pectate lyase secretion and extracellular activity, while overexpression of CcpelA in the Si-60 isolate increases its aggressiveness and PL secretion, overview	Colletotrichum coccodes
physiological function	role of secreted pectate lyase, a cell wall-degrading enzyme, in the aggressiveness of Colletotrichum coccodes, overview	Colletotrichum coccodes