Literature summary for 4.2.2.1 extracted from

Nazipi, S.; Stodkilde-Jorgensen, K.; Scavenius, C.; Brueggemann, H.
The skin bacterium Propionibacterium acnes employs two variants of hyaluronate lyase with distinct properties (2017), Microorganisms, 5, 57 .

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Organism

Organism	UniProt	Comment	Textmining
Cutibacterium acnes	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

General Information

General Information	Comment	Organism
physiological function	bacterium employs two distinct variants of hyaluronan lyases. Variant HYL-IB/II is highly active, resulting in complete hyaluronan degradation. It is present in strains of the phylotypes IB and II. Variant HYL-IA has low activity, resulting in incomplete hyaluronan degradation. It is present in type IA strains. Type IA strains are primarily found on the skin surface and associated with acne vulgaris, type IB/II strains are more often associated with soft and deep tissue infections	Cutibacterium acnes

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Release 2023.1 (January 2023)