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Literature summary for 4.2.2.1 extracted from

  • Hynes, W.; Johnson, C.; Stokes, M.
    A single nucleotide mutation results in loss of enzymatic activity in the hyaluronate lyase gene of Streptococcus pyogenes (2009), Microb. Pathog., 47, 308-313.
    View publication on PubMed
Search for more literature for 4.2.2.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli TOP10 Streptococcus pyogenes serotype M4
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS10750
expressed in Escherichia coli TOP10 Streptococcus pyogenes serotype M1
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS5005
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS10270
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS315
expressed in Escherichia coli TOP10 Streptococcus pyogenes serotype M3
expressed in Escherichia coli TOP10 Streptococcus pyogenes str. Manfredo
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS10394
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS9429
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS8232
expressed in Escherichia coli TOP10 Streptococcus pyogenes MGAS6180
expressed in Escherichia coli TOP10 Streptococcus pyogenes NZ131
expressed in Escherichia coli TOP10 Streptococcus pyogenes

Protein Variants

Protein Variants Comment Organism
D199V loss of activity Streptococcus pyogenes
V199D gain of enzymatic activity from a previously inactive protein, numbering based on the sequence of HylA from strain 10403 (M-22) Streptococcus pyogenes serotype M1
V199D mutant and wild-type protein have no enzymatic activity, numbering based on the sequence of HylA from strain 10403 (M-22) Streptococcus pyogenes serotype M3

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes A7XFU3 M-22 strain 6219
-
Streptococcus pyogenes A7XFU4 M-22 strain 3200
-
Streptococcus pyogenes A7XFV0 M-22 strain 4786
-
Streptococcus pyogenes A7XFV1 M-22 strain 437
-
Streptococcus pyogenes Q9L7W9 M-22, strain 10403
-
Streptococcus pyogenes MGAS10270
-
-
-
Streptococcus pyogenes MGAS10394
-
-
-
Streptococcus pyogenes MGAS10750
-
-
-
Streptococcus pyogenes MGAS315
-
-
-
Streptococcus pyogenes MGAS5005
-
-
-
Streptococcus pyogenes MGAS6180
-
-
-
Streptococcus pyogenes MGAS8232
-
-
-
Streptococcus pyogenes MGAS9429
-
-
-
Streptococcus pyogenes NZ131
-
-
-
Streptococcus pyogenes serotype M1 Q99ZX4
-
-
Streptococcus pyogenes serotype M1 SF370 Q99ZX4
-
-
Streptococcus pyogenes serotype M3 A7XFU7
-
-
Streptococcus pyogenes serotype M3 A7XFU8
-
-
Streptococcus pyogenes serotype M3 A7XFU9
-
-
Streptococcus pyogenes serotype M3 A7XFV3
-
-
Streptococcus pyogenes serotype M3 A7XFV4
-
-
Streptococcus pyogenes serotype M3 A7XFV6
-
-
Streptococcus pyogenes serotype M3 A7XFV7
-
-
Streptococcus pyogenes serotype M3 1020 A7XFV6
-
-
Streptococcus pyogenes serotype M3 1055 A7XFU7
-
-
Streptococcus pyogenes serotype M3 350 A7XFU8
-
-
Streptococcus pyogenes serotype M3 3779 A7XFV7
-
-
Streptococcus pyogenes serotype M3 422 A7XFU9
-
-
Streptococcus pyogenes serotype M3 872 A7XFV3
-
-
Streptococcus pyogenes serotype M3 94146 A7XFV4
-
-
Streptococcus pyogenes serotype M4 A7XFU5
-
-
Streptococcus pyogenes serotype M4 A7XFU6
-
-
Streptococcus pyogenes serotype M4 A7XFV2
-
-
Streptococcus pyogenes serotype M4 A7XFV5
-
-
Streptococcus pyogenes serotype M4 2397 A7XFV5
-
-
Streptococcus pyogenes serotype M4 4282 A7XFV2
-
-
Streptococcus pyogenes serotype M4 4283 A7XFU5
-
-
Streptococcus pyogenes serotype M4 445 A7XFU6
-
-
Streptococcus pyogenes str. Manfredo
-
-
-

Synonyms

Synonyms Comment Organism
hyaluronate lyase HylA
-
 Streptococcus pyogenes serotype M4
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS10750
hyaluronate lyase HylA
-
 Streptococcus pyogenes serotype M1
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS5005
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS10270
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS315
hyaluronate lyase HylA
-
 Streptococcus pyogenes serotype M3
hyaluronate lyase HylA
-
 Streptococcus pyogenes str. Manfredo
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS10394
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS9429
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS8232
hyaluronate lyase HylA
-
 Streptococcus pyogenes MGAS6180
hyaluronate lyase HylA
-
 Streptococcus pyogenes NZ131
hyaluronate lyase HylA
-
 Streptococcus pyogenes