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Literature summary for 4.2.2.1 extracted from

  • Mishra, P.; Bhakuni, V.
    Self-assembly of bacteriophage-associated hyaluronate lyase (HYLP2) into an enzymatically active fibrillar film (2009), J. Biol. Chem., 284, 5240-5249.
    View publication on PubMed
Search for more literature for 4.2.2.1

Cloned(Commentary)

Cloned (Comment) Organism
-
 Streptococcus pyogenes phage H10403

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000
-
 gel filtration Streptococcus pyogenes phage H10403

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes phage H10403
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptococcus pyogenes phage H10403

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chondroitin sulfate
-
 Streptococcus pyogenes phage H10403 ?
-
 ?
hyaluronic acid
-
 Streptococcus pyogenes phage H10403 ?
-
 ?

Subunits

Subunits Comment Organism
homotrimer pH 7.0, aggregation at pH 5.0, gel filtration, SDS-PAGE after chemical cross-linking Streptococcus pyogenes phage H10403

Synonyms

Synonyms Comment Organism
hyaluronate lyase HylP2
-
 Streptococcus pyogenes phage H10403

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 chondroitin sulfate after 14 h at pH 5.0 (fibrillar film formation) 20% activity (100% activity at pH 7.0, 0 h, with hyaluronic acid) Streptococcus pyogenes phage H10403
additional information
-
 hyaluronic acid after 15 h at pH 5.0 (fibrillar film formation) 68% activity (100% activity at pH 7.0, 0 h, with hyaluronic acid) Streptococcus pyogenes phage H10403