BRENDA - Enzyme Database show
show all sequences of 4.2.2.1

Inhibition of hyaluronidases and chondroitinases by fatty acids

Suzuki, K.; Terasaki, Y.; Uyeda, M.; J. Enzyme Inhib. Med. Chem. 17, 183-186 (2002)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
(13Z)-docos-13-enoic acid
strong inhibition
Streptococcus dysgalactiae
(13Z)-docos-13-enoic acid
weak inhibition
Streptomyces hyalurolytics
arachidic acid
weak inhibition
Streptococcus dysgalactiae
arachidic acid
weak inhibition
Streptomyces hyalurolytics
behenic acid
weak inhibition
Streptococcus dysgalactiae
behenic acid
weak inhibition
Streptomyces hyalurolytics
capric acid
weak inhibition
Streptococcus dysgalactiae
capric acid
weak inhibition
Streptomyces hyalurolytics
eicosadienoic acid
strong inhibition
Streptococcus dysgalactiae
eicosadienoic acid
weak inhibition
Streptomyces hyalurolytics
eicosanoic acid
strong inhibition
Streptococcus dysgalactiae
eicosanoic acid
weak inhibition
Streptomyces hyalurolytics
eicosapentaenoic acid
strong inhibition
Streptococcus dysgalactiae
eicosapentaenoic acid
weak inhibition
Streptomyces hyalurolytics
eicosatetraenoic acid
strong inhibition
Streptococcus dysgalactiae
eicosatetraenoic acid
weak inhibition
Streptomyces hyalurolytics
eicosatrienoic acid
strong inhibition
Streptococcus dysgalactiae
eicosatrienoic acid
weak inhibition
Streptomyces hyalurolytics
elaidic acid
-
Streptococcus dysgalactiae
elaidic acid
weak inhibition
Streptomyces hyalurolytics
lauric acid
weak inhibition
Streptococcus dysgalactiae
lauric acid
weak inhibition
Streptomyces hyalurolytics
linoleic acid
-
Streptococcus dysgalactiae
linoleic acid
weak inhibition
Streptomyces hyalurolytics
linolenic acid
-
Streptococcus dysgalactiae
linolenic acid
weak inhibition
Streptomyces hyalurolytics
methyl (9Z)-octadecenoate
-
Streptococcus dysgalactiae
methyl (9Z)-octadecenoate
weak inhibition
Streptomyces hyalurolytics
myristic acid
weak inhibition
Streptococcus dysgalactiae
myristic acid
weak inhibition
Streptomyces hyalurolytics
myristoleic acid
-
Streptococcus dysgalactiae
myristoleic acid
weak inhibition
Streptomyces hyalurolytics
nervonic acid
strong inhibition
Streptococcus dysgalactiae
nervonic acid
weak inhibition
Streptomyces hyalurolytics
oleic acid
-
Streptococcus dysgalactiae
oleic acid
weak inhibition
Streptomyces hyalurolytics
palmitic acid
weak inhibition
Streptococcus dysgalactiae
palmitic acid
weak inhibition
Streptomyces hyalurolytics
palmitoleic acid
-
Streptococcus dysgalactiae
palmitoleic acid
weak inhibition
Streptomyces hyalurolytics
petroselinic acid
strong inhibition
Streptococcus dysgalactiae
petroselinic acid
weak inhibition
Streptomyces hyalurolytics
ricinoleic acid
-
Streptococcus dysgalactiae
ricinoleic acid
weak inhibition
Streptomyces hyalurolytics
stearic acid
weak inhibition
Streptococcus dysgalactiae
stearic acid
weak inhibition
Streptomyces hyalurolytics
vaccenic acid
strong inhibition
Streptococcus dysgalactiae
vaccenic acid
weak inhibition
Streptomyces hyalurolytics
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptococcus dysgalactiae
-
-
-
Streptomyces hyalurolytics
-
-
-
Reaction
Reaction
Commentary
Organism
Cleaves hyaluronate chains at a beta-D-GalNAc-(1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
also acts on chondroitin, the product is more systematically known as 3-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose
Streptomyces hyalurolytics
Cleaves hyaluronate chains at a beta-D-GalNAc-(1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
also acts on chondroitin, the product is more systematically known as 3-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose
Streptococcus dysgalactiae
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
hyaluronic acid
from pig skin
652640
Streptococcus dysgalactiae
?
-
-
-
?
hyaluronic acid
from pig skin
652640
Streptomyces hyalurolytics
3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
-
-
-
?
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
37
-
assay at
Streptococcus dysgalactiae
60
-
assay at
Streptomyces hyalurolytics
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.2
-
phosphate buffer, assay at
Streptococcus dysgalactiae
6.2
-
phosphate buffer, assay at
Streptomyces hyalurolytics
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
additional information
-
additional information
-
Streptococcus dysgalactiae
additional information
-
additional information
-
Streptomyces hyalurolytics
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
(13Z)-docos-13-enoic acid
strong inhibition
Streptococcus dysgalactiae
(13Z)-docos-13-enoic acid
weak inhibition
Streptomyces hyalurolytics
arachidic acid
weak inhibition
Streptococcus dysgalactiae
arachidic acid
weak inhibition
Streptomyces hyalurolytics
behenic acid
weak inhibition
Streptococcus dysgalactiae
behenic acid
weak inhibition
Streptomyces hyalurolytics
capric acid
weak inhibition
Streptococcus dysgalactiae
capric acid
weak inhibition
Streptomyces hyalurolytics
eicosadienoic acid
strong inhibition
Streptococcus dysgalactiae
eicosadienoic acid
weak inhibition
Streptomyces hyalurolytics
eicosanoic acid
strong inhibition
Streptococcus dysgalactiae
eicosanoic acid
weak inhibition
Streptomyces hyalurolytics
eicosapentaenoic acid
strong inhibition
Streptococcus dysgalactiae
eicosapentaenoic acid
weak inhibition
Streptomyces hyalurolytics
eicosatetraenoic acid
strong inhibition
Streptococcus dysgalactiae
eicosatetraenoic acid
weak inhibition
Streptomyces hyalurolytics
eicosatrienoic acid
strong inhibition
Streptococcus dysgalactiae
eicosatrienoic acid
weak inhibition
Streptomyces hyalurolytics
elaidic acid
-
Streptococcus dysgalactiae
elaidic acid
weak inhibition
Streptomyces hyalurolytics
lauric acid
weak inhibition
Streptococcus dysgalactiae
lauric acid
weak inhibition
Streptomyces hyalurolytics
linoleic acid
-
Streptococcus dysgalactiae
linoleic acid
weak inhibition
Streptomyces hyalurolytics
linolenic acid
-
Streptococcus dysgalactiae
linolenic acid
weak inhibition
Streptomyces hyalurolytics
methyl (9Z)-octadecenoate
-
Streptococcus dysgalactiae
methyl (9Z)-octadecenoate
weak inhibition
Streptomyces hyalurolytics
myristic acid
weak inhibition
Streptococcus dysgalactiae
myristic acid
weak inhibition
Streptomyces hyalurolytics
myristoleic acid
-
Streptococcus dysgalactiae
myristoleic acid
weak inhibition
Streptomyces hyalurolytics
nervonic acid
strong inhibition
Streptococcus dysgalactiae
nervonic acid
weak inhibition
Streptomyces hyalurolytics
oleic acid
-
Streptococcus dysgalactiae
oleic acid
weak inhibition
Streptomyces hyalurolytics
palmitic acid
weak inhibition
Streptococcus dysgalactiae
palmitic acid
weak inhibition
Streptomyces hyalurolytics
palmitoleic acid
-
Streptococcus dysgalactiae
palmitoleic acid
weak inhibition
Streptomyces hyalurolytics
petroselinic acid
strong inhibition
Streptococcus dysgalactiae
petroselinic acid
weak inhibition
Streptomyces hyalurolytics
ricinoleic acid
-
Streptococcus dysgalactiae
ricinoleic acid
weak inhibition
Streptomyces hyalurolytics
stearic acid
weak inhibition
Streptococcus dysgalactiae
stearic acid
weak inhibition
Streptomyces hyalurolytics
vaccenic acid
strong inhibition
Streptococcus dysgalactiae
vaccenic acid
weak inhibition
Streptomyces hyalurolytics
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
additional information
-
additional information
-
Streptococcus dysgalactiae
additional information
-
additional information
-
Streptomyces hyalurolytics
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
hyaluronic acid
from pig skin
652640
Streptococcus dysgalactiae
?
-
-
-
?
hyaluronic acid
from pig skin
652640
Streptomyces hyalurolytics
3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
-
-
-
?
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
37
-
assay at
Streptococcus dysgalactiae
60
-
assay at
Streptomyces hyalurolytics
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.2
-
phosphate buffer, assay at
Streptococcus dysgalactiae
6.2
-
phosphate buffer, assay at
Streptomyces hyalurolytics
Other publictions for EC 4.2.2.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
748535
Mai
Modelling hyaluronan degradat ...
Streptococcus pneumoniae
Mathr. Biosci.
303
126-138
2018
-
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2
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1
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749208
Kasparova
-
Magnetic macroporous bead cel ...
Streptococcus pneumoniae
Process Biochem.
72
105-111
2018
-
1
1
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1
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746795
Zhu
Purification and characteriza ...
Arthrobacter globiformis, Arthrobacter globiformis A152
Appl. Biochem. Biotechnol.
182
216-228
2017
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8
1
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6
1
1
2
2
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1
1
1
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747455
Tao
New insights into the action ...
Pedobacter heparinus
Carbohydr. Polym.
158
85-92
2017
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748621
Nazipi
The skin bacterium Propioniba ...
Cutibacterium acnes
Microorganisms
5
57
2017
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1
1
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747436
Haas
Hyaluronate lyase activity of ...
Streptococcus suis
BMC Res. Notes
8
722
2015
-
1
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5
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1
1
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747621
Sun
Genetic and functional charac ...
Streptococcus equi subsp. zooepidemicus
Curr. Microbiol.
70
35-42
2015
-
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1
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1
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2
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1
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748434
Li
Functional role of R462 in th ...
Streptococcus pneumoniae
J. Mol. Model.
21
196
2015
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2
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748522
Kurata
Hyaluronate lyase of a deep-s ...
Bacillus niacini, Bacillus niacini JAM F8
Mar. Biotechnol.
17
277-284
2015
-
-
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6
-
1
4
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6
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8
1
1
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2
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1
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2
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749307
Shukla
The C-terminus hot spot regio ...
Streptococcus pyogenes phage
Sci. Rep.
5
14429
2015
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3
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749411
Yusof
Hyaluronatelyase production b ...
Streptococcus pneumoniae
Trop. Biomed.
32
413-418
2015
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1
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729322
Singh
Characterization of hyaluronic ...
Streptococcus pyogenes phage H4489A
Biochimie
102
203-210
2014
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1
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6
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2
4
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2
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5
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1
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1
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3
3
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728911
Khan
Crystallization and preliminar ...
Streptococcus suis
Acta Crystallogr. Sect. F
69
673-675
2013
-
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1
1
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5
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730258
Zheng
Catalytic mechanism of hyaluro ...
Streptococcus pneumoniae
J. Phys. Chem. B
117
10161-10172
2013
-
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3
3
-
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730253
Zheng
Initial events in the degradat ...
Streptococcus pneumoniae
J. Phys. Chem. B
116
11166-11172
2012
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1
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2
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714651
El-Safory
Characterization of hyaluronat ...
Streptococcus pyogenes phage H4489A
Carbohydr. Polym.
84
1182-1191
2011
-
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1
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8
1
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1
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1
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8
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1
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1
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1
1
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714907
Braun
Design of benzimidazole- and b ...
Streptococcus agalactiae, Streptococcus agalactiae 4755
Eur. J. Med. Chem.
46
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2010
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Self-assembly of bacteriophage ...
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705539
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The Streptococcus equi prophag ...
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Microbiology
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1
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2
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1
1
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1
1
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706651
Joshi
Domain motions of hyaluronan l ...
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2009
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Intratumoral coadministration ...
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694569
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Anti-atherosclerotic effect of ...
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Pharmazie
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2008
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1
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1
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4
1
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677586
Tufto
The effect of collagenase and ...
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677946
Akhtar
Role of ionic interactions and ...
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1
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1
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664596
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1
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4
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1
2
1
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1
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2
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2
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1
1
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2
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8
2
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679044
Yang
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Purification of recombinant hy ...
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1
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1
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1
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1
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1
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1
1
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679928
Taylor
Comparison of bovine- and reco ...
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680038
Rigden
Design of new benzoxazole-2-th ...
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Glycobiology
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757-765
2006
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6
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6
8
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Akhtar
Insights into the mechanism of ...
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1
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1
1
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1
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-
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-
-
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666687
Salmen
Sulphated oligosaccharides as ...
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7
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4
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1
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1
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4
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4
7
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2
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1
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4
-
1
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-
1
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666893
Botzki
-
Structure-based design of bact ...
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458-469
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1
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1
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3
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1
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3
4
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1
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-
-
-
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-
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664514
Maccari
-
High-performance capillary ele ...
Streptomyces hyalurolyticus
Carbohydr. Polym.
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55-63
2004
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-
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1
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1
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1
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1
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1
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Kuehn
Complementary exploration of t ...
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1
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Akhtar
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Streptococcus pneumoniae hyalu ...
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2
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2
2
1
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6
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4
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2
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2
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665318
Wangun
Anti-inflammatory and anti-hya ...
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755-758
2004
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4
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1
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2
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665374
King
Distribution, genetic diversit ...
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4740-4747
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1
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17
-
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17
-
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-
-
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-
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17
-
17
-
-
-
-
-
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-
-
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666251
Allen
Identification and characteris ...
Streptococcus suis
Microb. Pathog.
36
327-335
2004
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1
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1
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2
2
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1
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3
1
1
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1
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1
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1
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2
2
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1
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3
1
1
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-
-
1
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666265
Makris
The hyaluronate lyase of Staph ...
Staphylococcus aureus, Staphylococcus aureus NCTC 8325
Microbiology
150
2005-2013
2004
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1
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1
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6
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652643
Okorukwu
Effects of ascorbic acid and a ...
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377-382
2003
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6
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1
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1
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652762
de Assis
Biosynthesis of chondroitinase ...
Paracoccidioides brasiliensis
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52
479-481
2003
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655502
Oettl
Comparative characterization o ...
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2003
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1
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2
1
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-
656140
Akhtar
Streptococcus pneumoniae hyalu ...
Streptococcus pneumoniae
J. Biol. Chem.
278
25509-25516
2003
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1
1
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1
7
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2
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7
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2
2
1
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2
-
1
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-
656150
Nukui
The function of hydrophobic re ...
Streptococcus pneumoniae
J. Biol. Chem.
278
3079-3088
2003
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1
1
5
-
1
5
1
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5
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5
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1
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5
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4
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1
1
1
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1
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-
656185
Rigden
Structures of Streptococcus pn ...
Streptococcus pneumoniae
J. Biol. Chem.
278
50596-50606
2003
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1
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5
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652640
Suzuki
Inhibition of hyaluronidases a ...
Streptococcus dysgalactiae, Streptomyces hyalurolytics
J. Enzyme Inhib. Med. Chem.
17
183-186
2002
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48
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2
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2
-
2
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2
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-
-
-
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654497
Baker
The hyaluronan lyase of Strept ...
Streptococcus pyogenes phage H4489A
Biochem. J.
365
317-322
2002
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1
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1
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6
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3
1
1
-
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1
1
-
-
1
-
-
-
-
-
-
656063
Jedrzejas
Mechanism of hyaluronan degrad ...
Streptococcus pneumoniae
J. Biol. Chem.
277
28287-28297
2002
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1
1
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1
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4
-
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656077
Mello
Structure and flexibility of S ...
Streptococcus agalactiae
J. Biol. Chem.
277
36678-36688
2002
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1
1
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3
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3
2
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655681
Kelly
Kinetic properties of Streptoc ...
Streptococcus pneumoniae
Glycobiology
11
297-304
2001
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1
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6
1
1
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1
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2
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1
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1
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655682
Suzuki
Preparation and inhibitory act ...
Streptomyces hyalurolyticus
Glycobiology
11
57-64
2001
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1
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1
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1
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1
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655996
Li
Vitamin C inhibits the enzymat ...
Streptococcus pneumoniae
J. Biol. Chem.
276
15125-15130
2001
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1
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1
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1
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656026
Li
Hyaluronan binding and degrada ...
Streptococcus agalactiae
J. Biol. Chem.
276
41407-41416
2001
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1
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3
1
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654042
Jedrzejas
Structural studies of streptoc ...
Streptococcus agalactiae
Acta Crystallogr. Sect. D
56
460-463
2000
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1
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654478
Baker
-
Action pattern and substrate s ...
Streptococcus sp.
Biochem. J.
348
465-471
2000
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655324
Li
Structural basis of hyaluronan ...
Streptococcus pneumoniae
EMBO J.
19
1228-1240
2000
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1
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1
1
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655596
Hynes
Hyaluronidases of Gram-positiv ...
Aeromonas sp., Bacteroides fragilis, Bacteroides ovatus, Bacteroides vulgatus, Candida albicans, Candida parapsilosis, Candida tropicalis, Clostridioides difficile, Clostridium chauvoei, Clostridium perfringens, Clostridium septicum, Cutibacterium acnes, Cutibacterium granulosum, Fusobacterium mortiferum, Meyerozyma guilliermondii, Pichia kudriavzevii, Porphyromonas asaccharolytica, Prevotella melaninogenica, Staphylococcus aureus, Staphylococcus hyicus, Streptococcus agalactiae, Streptococcus constellatus, Streptococcus dysgalactiae, Streptococcus equi, Streptococcus intermedius, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus uberis, Streptomyces coelicolor, Streptomyces griseus, Streptomyces hyalurolyticus, Treponema pallidum, Treponema pallidum subsp. pertenue
FEMS Microbiol. Lett.
183
201-207
2000
1
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33
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5
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66
5
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656480
Ponnuraj
Mechanism of hyaluronan bindin ...
Streptococcus pneumoniae
J. Mol. Biol.
299
885-895
2000
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1
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2
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657325
Pritchard
Characterization of the active ...
Streptococcus agalactiae
Proteins Struct. Funct. Genet.
40
126-134
2000
-
-
1
-
50
-
2
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1
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4
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1
1
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1
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1
1
1
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1
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1
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50
-
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2
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1
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1
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1
-
1
1
1
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-
1
-
-
-
-
-
-
-
-
-
210746
Gase
The Streptococcus agalactiae h ...
Streptococcus agalactiae 4755, Streptococcus agalactiae
Biochim. Biophys. Acta
1398
86-98
1998
-
-
1
-
-
-
-
-
-
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11
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1
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2
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1
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1
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210748
Jedrzejas
Crystallization and preliminar ...
Streptococcus pneumoniae
J. Struct. Biol.
121
73-75
1998
-
-
-
1
-
-
-
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2
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1
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1
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-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210749
Jedrzejas
Expression and purification of ...
Streptococcus pneumoniae
Protein Expr. Purif.
13
83-89
1998
-
-
-
-
-
-
-
1
1
-
3
-
-
3
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1
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1
1
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1
1
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-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210747
Steiner
Cloning and sequencing of the ...
Cutibacterium acnes
Can. J. Microbiol.
43
315-321
1997
-
-
1
-
-
-
-
-
-
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6
-
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1
1
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1
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-
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-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210750
Pritchard
Characterization of the group ...
Streptococcus sp.
Arch. Biochem. Biophys.
315
431-437
1994
-
-
-
-
-
-
-
-
-
-
-
-
-
3
1
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-
-
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-
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-
1
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1
-
-
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210745
Bautista
-
Effects of discharged fraction ...
Streptococcus dysgalactiae subsp. equisimilis, Streptococcus dysgalactiae subsp. equisimilis SHL-03
J. Ferment. Technol.
64
419-424
1986
-
-
-
-
-
1
-
-
-
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2
-
-
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-
-
-
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2
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-
-
1
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-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210744
Arvidson
-
Extracellular enzymes from Sta ...
Staphylococcus aureus
Staphylococci and Staphylococcal infections (Easmon, C. S. F. ; Adlam, C. , ed. )
2
745-808
1983
-
-
-
1
-
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5
-
1
-
1
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1
-
-
-
-
-
-
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1
1
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-
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1
-
1
-
-
-
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-
-
-
-
-
-
1
-
-
-
5
-
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1
-
1
-
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-
-
-
-
-
-
1
1
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
210751
Cove
Effects of oxygen concentratio ...
Cutibacterium acnes, Cutibacterium granulosum
J. Gen. Microbiol.
129
3327-3334
1983
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
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-
-
-
-
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2
-
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-
-
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-
-
-
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-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210735
Ozegowski
-
Reinigung und Charakterisierun ...
Streptococcus dysgalactiae subsp. equisimilis
Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg.
249
310-322
1981
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
2
-
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-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210736
Ingham
Purification and partial chara ...
Cutibacterium acnes
J. Gen. Microbiol.
115
411-418
1979
-
-
-
-
-
-
-
-
-
-
2
-
-
2
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1
-
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1
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3
1
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1
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1
-
3
-
-
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-
-
-
-
-
-
-
-
-
-
-
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-
2
-
-
-
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1
-
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1
-
3
1
-
-
1
-
1
-
3
-
-
-
-
-
-
-
210737
Hill
Purification and properties of ...
Streptococcus sp.
Infect. Immun.
14
726-735
1976
-
-
-
-
-
1
-
1
-
-
2
-
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2
-
1
1
-
-
-
1
1
1
1
-
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1
-
1
1
3
-
-
-
-
-
-
-
-
-
-
1
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-
-
1
-
-
2
-
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1
1
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-
1
1
1
1
-
-
1
-
1
1
3
-
-
-
-
-
-
-
210738
Abramson
Staphylococcal hyaluronate lya ...
Staphylococcus aureus
Contrib. Microbiol. Immunol.
1
376-389
1973
-
-
-
1
-
-
-
1
-
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1
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1
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1
1
-
-
-
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1
1
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4
-
2
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3
-
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1
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-
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1
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-
1
-
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1
1
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-
-
1
1
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-
-
4
-
2
-
3
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-
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210739
Rautela
Crystallization and partial ch ...
Staphylococcus aureus 1801, Staphylococcus aureus
Arch. Biochem. Biophys.
158
687-694
1973
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1
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1
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3
-
1
1
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-
-
-
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2
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-
-
-
-
-
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-
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-
-
-
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-
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1
-
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-
-
-
-
-
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1
-
-
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1
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
210740
Gerlach
-
Hyaluronatlyase von Streptococ ...
Streptococcus pyogenes
Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg.
221
296-302
1972
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-
-
-
-
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1
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-
1
-
-
1
-
-
-
1
1
1
-
-
-
1
-
1
1
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
1
1
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
210741
Gerlach
-
Hyaluronatlyase von Streptococ ...
Streptococcus pyogenes
Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg.
221
166-172
1972
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-
-
-
-
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-
-
-
-
-
-
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1
-
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1
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-
-
1
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1
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-
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-
-
-
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-
-
-
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1
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1
-
1
-
-
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-
-
-
-
-
-
-
-
-
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-
210742
Vesterberg
Studies on extracellular prote ...
Staphylococcus aureus, Staphylococcus aureus M18
Biochim. Biophys. Acta
168
218-227
1968
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-
-
-
-
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3
-
1
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-
-
-
3
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-
-
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2
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1
1
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-
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3
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1
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2
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1
1
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-
210743
Abramson
Staphylococcal hyaluronate lya ...
Staphylococcus aureus, Staphylococcus aureus AEMC 1801
J. Bacteriol.
96
886-892
1968
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1
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2
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1
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1
2
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3
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2
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1
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1
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1
2
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3
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2
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