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Literature summary for 4.2.1.94 extracted from

  • Basarab, G.S.; Steffens, J.J.; Wawrzak, Z.; Schwartz, R.S.; Lundqvist, T.; Jordan, D.B.
    Catalytic mechanism of scytalone dehydratase: site-directed mutagenisis, kinetic isotope effects, and alternate substrates (1999), Biochemistry, 38, 6012-6024.
    View publication on PubMed
Search for more literature for 4.2.1.94

Protein Variants

Protein Variants Comment Organism
additional information kinetic data of several point mutants Pyricularia grisea

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information Km values and kinetic konstants of several mutants Pyricularia grisea
15
-
 2,3-Dihydro-2,5-dihydroxy-4H-benzopyran-4-one 25°C, pH 7.0 Pyricularia grisea
31
-
 vermelone 25°C, pH 7.0 Pyricularia grisea
33
-
 Scytalone 25°C, pH 7.0 Pyricularia grisea

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
scytalone Pyricularia grisea
-
 1,3,8-trihydroxynaphthalene + H2O
-
 r

Organism

Organism UniProt Comment Textmining
Pyricularia grisea
-
-
-

Reaction

Reaction Comment Organism Reaction ID
scytalone = 1,3,8-trihydroxynaphthalene + H2O syn elimination mechanism Pyricularia grisea
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one
-
 Pyricularia grisea 5-hydroxy-4H-benzopyran-4-one + H2O
-
 r
scytalone
-
 Pyricularia grisea 1,3,8-trihydroxynaphthalene + H2O
-
 r
vermelone
-
 Pyricularia grisea 1,8-dihydroxynaphthalene + H2O
-
 r