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Literature summary for 4.2.1.92 extracted from

  • Hamberg, M.; Gerwick, W.H.
    Biosynthesis of vicinal dihydroxy fatty acids in the red alga Gracilariopsis menaneiformis: Identification of a sodium-dependent 12-lipoxygenase and a hydroperxide isomerase (1993), Arch. Biochem. Biophys., 305, 115-122.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
nordihydroguaiaretic acid
-
Gracilariopsis lemaneiformis

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information equally distributed between the high speed supernatant and particulate fractions Gracilariopsis lemaneiformis
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000 45000 gel filtration, 2 bands of enzyme activity, MW 220000 and MW 40000-45000 Gracilariopsis lemaneiformis
220000
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gel filtration, 2 bands of enzyme activity, MW 220000 and MW 40000-45000 Gracilariopsis lemaneiformis

Organism

Organism UniProt Comment Textmining
Gracilariopsis lemaneiformis
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid intramolecular oxygenation with retention of the configuration of the carbon atom hydroxylated Gracilariopsis lemaneiformis (8R)-hydroxy-(11R,12R)-epoxyeicosa-(5Z,9E,14Z)-trienoic acid + H2O
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