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Literature summary for 4.2.1.9 extracted from

  • Denina, I.; Paegle, L.; Prouza, M.; Holatko, J.; Patek, M.; Nesvera, J.; Ruklisha, M.
    Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum DeltailvA DeltapanB ilvNM13 (pECKAilvBNC) (2010), J. Ind. Microbiol. Biotechnol., 37, 689-699.
    View publication on PubMed
Search for more literature for 4.2.1.9

Protein Variants

Protein Variants Comment Organism
additional information construction of a relaxed rel deletion Corynebacterium glutamicum DELTAilvA DELTApanB DELTArel ilvNM13 (pECKAilvBNC) strain with the ilvBNC operon present on the multicopy plasmid pECKA Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-dihydroxy-3-methylbutanoate Corynebacterium glutamicum
-
 3-methyl-2-oxobutanoate + H2O i.e. 2-ketoisovalerate ?
2,3-dihydroxy-3-methylbutanoate Corynebacterium glutamicum ATCC 13032
-
 3-methyl-2-oxobutanoate + H2O i.e. 2-ketoisovalerate ?

Organism

Organism UniProt Comment Textmining
Corynebacterium glutamicum Q8NQZ9 gene ilvD
-
Corynebacterium glutamicum ATCC 13032 Q8NQZ9 gene ilvD
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-dihydroxy-3-methylbutanoate
-
 Corynebacterium glutamicum 3-methyl-2-oxobutanoate + H2O i.e. 2-ketoisovalerate ?
2,3-dihydroxy-3-methylbutanoate
-
 Corynebacterium glutamicum 3-methyl-2-oxobutanoate + H2O i.e. alpha-ketoisovalerate ?
2,3-dihydroxy-3-methylbutanoate
-
 Corynebacterium glutamicum ATCC 13032 3-methyl-2-oxobutanoate + H2O i.e. 2-ketoisovalerate ?
2,3-dihydroxy-3-methylbutanoate
-
 Corynebacterium glutamicum ATCC 13032 3-methyl-2-oxobutanoate + H2O i.e. alpha-ketoisovalerate ?
additional information reaction product determination by formation of 2,4-dinitrophenylhydrazone from the keto acid product resulting in 2-ketoisovalerate-dinitrophenylhydrazone Corynebacterium glutamicum ?
-
 ?
additional information reaction product determination by formation of 2,4-dinitrophenylhydrazone from the keto acid product resulting in 2-ketoisovalerate-dinitrophenylhydrazone Corynebacterium glutamicum ATCC 13032 ?
-
 ?

Synonyms

Synonyms Comment Organism
DHAD
-
 Corynebacterium glutamicum
dihydroxyacid dehydratase
-
 Corynebacterium glutamicum

General Information

General Information Comment Organism
metabolism DHAD is involved in the biosynthetic pathways of L-valine, L-isoleucine, L-leucine, and D-pantothenate, regulation, overview Corynebacterium glutamicum