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Literature summary for 4.2.1.79 extracted from

  • Reddick, J.J.; Sirkisoon, S.; Dahal, R.A.; Hardesty, G.; Hage, N.E.; Booth, W.T.; Quattlebaum, A.L.; Mills, S.N.; Meadows, V.G.; Adams, S.L.H.; Doyle, J.S.; Kiel, B.E.
    First biochemical characterization of a methylcitric acid cycle from Bacillus subtilis strain 168 (2017), Biochemistry, 56, 5698-5711 .
    View publication on PubMed
Search for more literature for 4.2.1.79

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21(DE3) Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2S,3S)-2-methylcitrate Escherichia coli the enzyme is involved in the methylcitric acid cycle cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate Bacillus subtilis the enzyme is involved in the methylcitric acid cycle cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate Bacillus subtilis 168 the enzyme is involved in the methylcitric acid cycle cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate Escherichia coli K12 the enzyme is involved in the methylcitric acid cycle cis-2-methylaconitate
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P45859
-
-
Bacillus subtilis 168 P45859
-
-
Escherichia coli P77243
-
-
Escherichia coli K12 P77243
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2S,3S)-2-methylcitrate the enzyme is involved in the methylcitric acid cycle Escherichia coli cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the enzyme is involved in the methylcitric acid cycle Bacillus subtilis cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the MmgE enzyme is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate Escherichia coli cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the MmgE enzyme is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate Bacillus subtilis cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the enzyme is involved in the methylcitric acid cycle Bacillus subtilis 168 cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the MmgE enzyme is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate Bacillus subtilis 168 cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the enzyme is involved in the methylcitric acid cycle Escherichia coli K12 cis-2-methylaconitate
-
 ?
(2S,3S)-2-methylcitrate the MmgE enzyme is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate Escherichia coli K12 cis-2-methylaconitate
-
 ?

Synonyms

Synonyms Comment Organism
2-methylcitrate dehydratase
-
 Escherichia coli
2-methylcitrate dehydratase
-
 Bacillus subtilis
mmgE
-
 Bacillus subtilis
PrpD
-
 Escherichia coli

General Information

General Information Comment Organism
metabolism the enzyme is involved in the methylcitric acid cycle Escherichia coli
metabolism the enzyme is involved in the methylcitric acid cycle Bacillus subtilis