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Literature summary for 4.2.1.78 extracted from

  • Berkner, H.; Engelhorn, J.; Liscombe, D.K.; Schweimer, K.; Woehrl, B.M.; Facchini, P.J.; Roesch, P.; Matecko, I.
    High-yield expression and purification of isotopically labeled norcoclaurine synthase, a Bet v 1-homologous enzyme, from Thalictrum flavum for NMR studies (2007), Protein Expr. Purif., 56, 197-204.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli is optimized Thalictrum flavum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21180
-
 mass spectrometry of recombinant Delta29NCS (coding for amino acids 30–210 of NCS) Thalictrum flavum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde Thalictrum flavum the enzyme is involved in the plant’s secondary metabolism and is required for the production of bioactive secondary metabolites like morphine (S)-Norcoclaurine + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Thalictrum flavum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Thalictrum flavum

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde the enzyme is involved in the plant’s secondary metabolism and is required for the production of bioactive secondary metabolites like morphine Thalictrum flavum (S)-Norcoclaurine + H2O
-
 ?

Synonyms

Synonyms Comment Organism
norcoclaurine synthase
-
 Thalictrum flavum