Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.56 extracted from

  • Chen, M.; Huang, X.; Zhong, C.; Li, J.; Lu, X.
    Identification of an itaconic acid degrading pathway in itaconic acid producing Aspergillus terreus (2016), Appl. Microbiol. Biotechnol., 100, 7541-7548 .
    View publication on PubMed
Search for more literature for 4.2.1.56

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 (DE3) Aspergillus terreus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Itaconyl-CoA + H2O Aspergillus terreus the enzyme is involved in the catabolic pathway of itaconic acid. Although Aspergillus terreus LYT10 can catabolize itaconic acid, it cannot grow in the medium using itaconic acid (with concentrations from 5 to 40 g/l) as the sole carbon source Citramalyl-CoA
-
 ?
Itaconyl-CoA + H2O Aspergillus terreus LYT10 the enzyme is involved in the catabolic pathway of itaconic acid. Although Aspergillus terreus LYT10 can catabolize itaconic acid, it cannot grow in the medium using itaconic acid (with concentrations from 5 to 40 g/l) as the sole carbon source Citramalyl-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus terreus A0A172ML99
-
-
Aspergillus terreus LYT10 A0A172ML99
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus terreus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Itaconyl-CoA + H2O
-
 Aspergillus terreus Citramalyl-CoA
-
 ?
Itaconyl-CoA + H2O the enzyme is involved in the catabolic pathway of itaconic acid. Although Aspergillus terreus LYT10 can catabolize itaconic acid, it cannot grow in the medium using itaconic acid (with concentrations from 5 to 40 g/l) as the sole carbon source Aspergillus terreus Citramalyl-CoA
-
 ?
Itaconyl-CoA + H2O
-
 Aspergillus terreus LYT10 Citramalyl-CoA
-
 ?
Itaconyl-CoA + H2O the enzyme is involved in the catabolic pathway of itaconic acid. Although Aspergillus terreus LYT10 can catabolize itaconic acid, it cannot grow in the medium using itaconic acid (with concentrations from 5 to 40 g/l) as the sole carbon source Aspergillus terreus LYT10 Citramalyl-CoA
-
 ?

Synonyms

Synonyms Comment Organism
IchA
-
 Aspergillus terreus

Expression

Organism Comment Expression
Aspergillus terreus upregulated at both transcription and protein levels, when 40 g/l of exogenous itaconic acid is added into the medium at the beginning of fermentation up

General Information

General Information Comment Organism
metabolism the enzyme is involved in the catabolic pathway of itaconic acid Aspergillus terreus