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Literature summary for 4.2.1.47 extracted from

  • Ayukawa, T.; Matsumoto, K.; Ishikawa, H.O.; Ishio, A.; Yamakawa, T.; Aoyama, N.; Suzuki, T.; Matsuno, K.
    Rescue of Notch signaling in cells incapable of GDP-L-fucose synthesis by gap junction transfer of GDP-L-fucose in Drosophila (2012), Proc. Natl. Acad. Sci. USA, 109, 15318-15323.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP-alpha-D-mannose Drosophila melanogaster
-
GDP-4-dehydro-alpha-D-rhamnose + H2O
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-alpha-D-mannose
-
Drosophila melanogaster GDP-4-dehydro-alpha-D-rhamnose + H2O
-
?

Synonyms

Synonyms Comment Organism
GDP-mannose 4,6 dehydratase
-
Drosophila melanogaster
GMD
-
Drosophila melanogaster

General Information

General Information Comment Organism
metabolism the enzyme is required for Fng-dependent Notch signaling and the fucosylation of bulk proteins Drosophila melanogaster