Inhibitors | Comment | Organism | Structure |
---|---|---|---|
TDP | 58% inhibition at 2 mM | Streptomyces peucetius | |
TDP | 62% inhibition at 2 mM | Streptomyces sp. C5 | |
TMP | 23% inhibition at 2 mM | Streptomyces peucetius | |
TMP | 25% inhibition at 2 mM | Streptomyces sp. C5 | |
TTP | 40% inhibition at 2 mM | Streptomyces peucetius | |
TTP | 37% inhibition at 2 mM | Streptomyces sp. C5 |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.019 | - |
NAD+ | - |
Streptomyces sp. C5 | |
0.02 | - |
NAD+ | - |
Streptomyces peucetius | |
0.031 | - |
dTDPglucose | - |
Streptomyces sp. C5 | |
0.035 | - |
dTDPglucose | - |
Streptomyces peucetius |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
2 * 36000, gel filtration, SDS-PAGE | Streptomyces peucetius |
39000 | - |
2 * 39000, gel filtration, SDS-PAGE | Streptomyces sp. C5 |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-glucose | Streptomyces peucetius | - |
? | - |
? | |
dTDP-glucose | Streptomyces sp. C5 | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces peucetius | - |
- |
- |
Streptomyces sp. C5 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces peucetius |
- |
Streptomyces sp. C5 |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.2 | - |
dTDPglucose | Streptomyces peucetius |
0.31 | - |
dTDPglucose | Streptomyces sp. C5 |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-glucose | - |
Streptomyces peucetius | ? | - |
? | |
dTDP-glucose | - |
Streptomyces sp. C5 | ? | - |
? | |
additional information | not: ADPglucose, ADPmannose, GDPmannose, GDPglucose, UDPgalactose | Streptomyces peucetius | ? | - |
? | |
additional information | not: ADPglucose, ADPmannose, GDPmannose, GDPglucose, UDPgalactose | Streptomyces sp. C5 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 36000, gel filtration, SDS-PAGE | Streptomyces peucetius |
dimer | 2 * 39000, gel filtration, SDS-PAGE | Streptomyces sp. C5 |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
dTDPglucose | Streptomyces sp. C5 |
7.8 | - |
dTDPglucose | Streptomyces peucetius |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Streptomyces peucetius | |
NAD+ | - |
Streptomyces sp. C5 |