Literature summary for 4.2.1.45 extracted from

Hey, A.E.; Elbein, A.D.
Biosynthesis of tyvelose. The purification and properties of cytidine diphosphate D-glucose oxidoreductase (1966), J. Biol. Chem., 241, 5473-5478.

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General Stability

General Stability	Organism
stable to freezing in all stages of purification	Salmonella enterica subsp. enterica serovar Typhimurium

Inhibitors

Inhibitors	Comment	Organism	Structure
p-chloromercuriphenylsulfonate	-	Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.4	-	CDP-D-glucose	-	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
6.4	-	-	Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CDP-D-glucose	-	Salmonella enterica subsp. enterica serovar Typhimurium	CDP-4-dehydro-6-deoxy-D-glucose + H2O	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.2	-	-	Salmonella enterica subsp. enterica serovar Typhimurium

pH Range

pH Minimum	pH Maximum	Comment	Organism
4.5	-	not active below	Salmonella enterica subsp. enterica serovar Typhimurium

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	required	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)