Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Fluorocitrate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | aconitase-specific activity increases by 42% at 2% O2 compared to 21% O2 | Rattus norvegicus | - |
heart | aconitase-specific activity increases by 12% at 2% O2 compared to 21% O2 | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cis-aconitate + H2O | - |
Rattus norvegicus | isocitrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aconitase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.007 | - |
pH 7.4, temperature not specified in the publication, tissue: brain | Rattus norvegicus | Fluorocitrate | |
0.012 | - |
pH 7.4, temperature not specified in the publication, tissue: heart | Rattus norvegicus | Fluorocitrate | |
0.024 | - |
pH 7.4, temperature not specified in the publication, tissue: kidney | Rattus norvegicus | Fluorocitrate | |
0.024 | - |
pH 7.4, temperature not specified in the publication, tissue: liver | Rattus norvegicus | Fluorocitrate |