Inhibitors | Comment | Organism | Structure |
---|---|---|---|
citramalate | an endogenous compound of fruit pulp, is a competitive endogenous inhibitor of citrus aconitase, it significantly increases citrate content and reduces the mitochondrial isozyme activity, while slightly inducing its protein level | Citrus limon | |
Oxalomalate | significantly increases citrate content and reduces the enzyme's activity, while slightly inducing its protein level. Specific activities of amino acid-metabolizing enzymes are induced in oxalomalate-treated callus cells, overview | Citrus limon |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | soluble isozyme | Citrus limon | 5829 | - |
mitochondrion | mitochondrial isozyme | Citrus limon | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Citrus limon | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
callus | from fruit juice cells | Citrus limon | - |
fruit | - |
Citrus limon | - |
Organism | Comment | Expression |
---|---|---|
Citrus limon | citramalate significantly increases citrate content and reduces the mitochondrial isozyme activity, while slightly inducing its protein level, oxalomalate also slightly upregulates the enzyme | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the increase in citrate, caused by aconitase inhibition, induces amino acid synthesis and the gamma-aminobutyrate shunt, in accordance with the suggested fate of citrate during the acid decline stage in citrus fruit | Citrus limon |