Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.28 extracted from

  • Toraya, T.; Uesaka, M.; Kondo, M.; Fukui, S.
    Dissociation of diol dehydrase into two different protein components (1973), Biochem. Biophys. Res. Commun., 52, 350-355.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide component S, 95% inhibition after pretreatment in 1 mM Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
formerly Aerobacter aerogenes
-

Oxidation Stability

Oxidation Stability Organism
oxygen lability only if components F and S are associated Klebsiella pneumoniae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-propanediol
-
Klebsiella pneumoniae propanal
-
?

Subunits

Subunits Comment Organism
More dissociation of protein into components S and F which are not identical with individual subunits, dissociation retarded by substrate, both components necessary for coenzyme binding Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
cobamide
-
Klebsiella pneumoniae