Protein Variants | Comment | Organism |
---|---|---|
R240A | mutant enzyme assembles into a metastable hexamer, which can undergo a reversible conversion to the octamer in the presence of substrate | Homo sapiens |
R240AS | metastable nature of the R240A hexamer | Homo sapiens |
W19A | assembles into a mixture of stable dimers | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
69600 | - |
mutant enzyme W19A, pH 7, analytical ultracentrifugation | Homo sapiens |
78600 | - |
mutant enzyme W19A, pH 7, dynamic light scattering | Homo sapiens |
183500 | - |
mutant enzyme R240A, pH 9, analytical ultracentrifugation | Homo sapiens |
188500 | - |
mutant enzyme R240A, pH 7, analytical ultracentrifugation | Homo sapiens |
197900 | - |
mutant enzyme F12L, pH 7, analytical ultracentrifugation | Homo sapiens |
212400 | - |
mutant enzyme R240A, pH 7, dynamic light scattering | Homo sapiens |
214400 | - |
mutant enzyme F12L, pH 7, dynamic light scattering | Homo sapiens |
244000 | - |
wild-type enzyme, pH 7, analytical ultracentrifugation | Homo sapiens |
317600 | - |
wild-type enzyme, pH 7, dynamic light scattering | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P13716 | - |
- |
Subunits | Comment | Organism |
---|---|---|
octamer | the enzyme is an obligate oligomer that can exist in functionally distinct quaternary states of different stoichiometries, which are called morpheeins, human PBGS assembles into long-lived morpheeins and is capable of forming either a high activity octamer or a low activity hexamer | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PBGS | - |
Homo sapiens |