Literature summary for 4.2.1.24 extracted from

Golombieski, R.M.; Graichen, D.A.; Pivetta, L.A.; Nogueira, C.W.; Loreto, E.L.; Rocha, J.B.
Diphenyl diselenide [(PhSe)(2)] inhibits Drosophila melanogaster delta-aminolevulinate dehydratase (delta-ALA-D) gene transcription and enzyme activity (2008), Comp. Biochem. Physiol. C Toxicol. Pharmacol., 147, 198-204.

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Inhibitors

Inhibitors	Comment	Organism	Structure
diphenyl diselenide	-	Mus musculus
Pb2+	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	swiss mice	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-aminolevulinate + 5-aminolevulinate	-	Mus musculus	porphobilinogen + 2 H2O	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.5	-	-	Mus musculus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.00195	-	37°C, pH 6.5	Mus musculus	diphenyl diselenide
0.0056	-	37°C, pH 8.5	Mus musculus	Pb2+
0.0062	-	37°C, pH 6.5	Mus musculus	Pb2+

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Release 2023.1 (January 2023)