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Literature summary for 4.2.1.24 extracted from

  • Soares, J.C.; Gabriel, D.; Folmer, V.; Augusti, G.R.; Rocha, J.B.
    High concentrations of glucose can activate or inhibit human erythrocyte aminolevulinate dehydratase in vitro depending exposure time (2006), Am. J. Biochem. Biotechnol., 2, 180-185.
No PubMed abstract available
Search for more literature for 4.2.1.24

Activating Compound

Activating Compound Comment Organism Structure
glucose incubations of erythrocytes for 24 h with glucose result in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
D-glucose incubations of erythrocytes for 24 h with glucose results in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-aminolevulinate + 5-aminolevulinate incubations of erythrocytes for 24 h with glucose result in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens porphobilinogen + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
delta-ALA-D
-
 Homo sapiens