Crystallization (Comment) | Organism |
---|---|
crystal structure of enzyme complexed with 4-oxosebaic acid and of enzyme complexed with 4,7-dioxosebaic acid | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4,7-dioxosebaic acid | - |
Escherichia coli | |
4-oxosebaic acid | active site-directed irreversible inhibitor, less potent than 4,7-dioxosebaic acid | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | enzyme uses a catalytic Zn2+ | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-aminolevulinate + 5-aminolevulinate | Escherichia coli | essential step in tetrapyrrole biosynthesis | porphobilinogen + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0ACB2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-aminolevulinate + 5-aminolevulinate | essential step in tetrapyrrole biosynthesis | Escherichia coli | porphobilinogen + 2 H2O | - |
? |