Literature summary for 4.2.1.22 extracted from

Prabhudesai, S.; Koceja, C.; Dey, A.; Eisa-Beygi, S.; Leigh, N.; Bhattacharya, R.; Mukherjee, P.; Ramchandran, R.
Cystathionine beta-synthase is necessary for axis development in vivo (2018), Front. Cell Dev. Biol., 6, 14 .

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Organism

Organism	UniProt	Comment	Textmining
Danio rerio	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	wide expression pattern for isoforms Cbsa and Cbsb primarily along the embryonic axis of the developing embryo	Danio rerio	-

General Information

General Information	Comment	Organism
physiological function	isoform Cbsb is responsible for anterior-posterior axis development, and Cbsa function is redundant. Cbsb loss of function fish embryos show shortened and bent axis, along with less H2S and more homocysteine	Danio rerio

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Release 2023.1 (January 2023)