Literature summary for 4.2.1.22 extracted from

Summers, C.M.; Hammons, A.L.; Mitchell, L.E.; Woodside, J.V.; Yarnell, J.W.; Young, I.S.; Evans, A.; Whitehead, A.S.
Influence of the cystathionine beta-synthase 844ins68 and methylenetetrahydrofolate reductase 677C>T polymorphisms on folate and homocysteine concentrations (2008), Eur. J. Hum. Genet., 16, 1010-1013.

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Protein Variants

Protein Variants	Comment	Organism
additional information	homocysteine levels in 5,10-methylenetetrahydrofolate reductase 677TT homozygotes who carry the cystathionine beta-synthase 844ins68 allele are significantly lower than in those who do not	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-serine + L-homocysteine	-	Homo sapiens	L-cystathionine + H2O	-	ir

Synonyms

Synonyms	Comment	Organism
CBS	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Homo sapiens

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Release 2023.1 (January 2023)