Cloned (Comment) | Organism |
---|---|
expression in yeast or in Escherichia coli | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.74 | - |
L-serine | pH 8.6 | Homo sapiens | |
6.11 | - |
L-cysteine | pH 8.6 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Cysteine + DL-homocysteine | full-length enzyme and truncated enzyme form lacking the C-terminal regulatory domain | Homo sapiens | Cystathionine + H2S | - |
? | |
L-Serine + homocysteine | - |
Homo sapiens | Cystathionine + H2O | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.13 | - |
L-cysteine | pH 8.6 | Homo sapiens | |
4.39 | - |
L-cysteine | pH 8.6 | Homo sapiens | |
10.2 | - |
L-serine | pH 8.6 | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | stimulates | Homo sapiens |