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Literature summary for 4.2.1.22 extracted from
- A novel cystathionine beta-synthase from Panagrellus redivivus (Nematoda) (1996), Int. J. Biochem. Cell Biol., 28, 543-549.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| beta-chloro-L-alanine | - |
Panagrellus redivivus |  |
| bithionol | - |
Panagrellus redivivus | |
| Cd2+ | - |
Panagrellus redivivus | |
| Cu3+ | - |
Panagrellus redivivus | |
| Dichlorophene | - |
Panagrellus redivivus | |
| Hexachlorophene | - |
Panagrellus redivivus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.13 | - |
L-Cys | - |
Panagrellus redivivus | |
| 1.72 | - |
2-mercaptoethanol | - |
Panagrellus redivivus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Panagrellus redivivus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | Na+, K+, Li+, Ca2+, Mg2+, Zn2+, Co2+, no effect on activity | Panagrellus redivivus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Serine + homocysteine | Panagrellus redivivus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Panagrellus redivivus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Panagrellus redivivus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 32 | - |
- |
Panagrellus redivivus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Cysteine + 2-mercaptoethanol | - |
Panagrellus redivivus | HOOC-CH(NH2)-CH2-S-CH2-CH2OH + H2S | - |
? | |
| L-Cysteine + DL-homocysteine | - |
Panagrellus redivivus | Cystathionine + H2S | - |
? | |
| L-Serine + homocysteine | - |
Panagrellus redivivus | Cystathionine + H2O | - |
? | |
| L-Serine + homocysteine | - |
Panagrellus redivivus | ? | - |
? | |
| additional information | no L-serine sulfhydrase activity | Panagrellus redivivus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 9 | - |
Panagrellus redivivus |
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